nagZ Triggers Gonococcal Biofilm Disassembly
نویسندگان
چکیده
منابع مشابه
D-amino acids trigger biofilm disassembly.
Bacteria form communities known as biofilms, which disassemble over time. In our studies outlined here, we found that, before biofilm disassembly, Bacillus subtilis produced a factor that prevented biofilm formation and could break down existing biofilms. The factor was shown to be a mixture of D-leucine, D-methionine, D-tyrosine, and D-tryptophan that could act at nanomolar concentrations. D-a...
متن کاملGonococcal cervicitis: a role for biofilm in pathogenesis.
Neisseria gonorrhoeae forms a biofilm in flow cells on glass coverslips as well as on primary cervical epithelial cells. Electron microscopic studies of cervical biopsy specimens from 10 patients with culture-proven N. gonorrhoeae infection revealed evidence of biofilm formation in 3 of the biopsy specimens. These biofilms showed gonococci in networks of bacterial membrane within the biofilm st...
متن کاملNorspermidine Is Not a Self-Produced Trigger for Biofilm Disassembly
Formation of Bacillus subtilis biofilms, consisting of cells encapsulated within an extracellular matrix of exopolysaccharide and protein, requires the polyamine spermidine. A recent study reported that (1) related polyamine norspermidine is synthesized by B. subtilis using the equivalent of the Vibrio cholerae biosynthetic pathway, (2) exogenous norspermidine at 25 μM prevents B. subtilis biof...
متن کاملA Review on Bacterial Biofilm Formation and Disassembly
The icaADBC gene was first identified in Staphylococcus epidermidis, and is also present in Staphylococcus aureus and other Staphylococcal species. PIA is produced by the gene products encoded by the icaADBC operon. Asymptomatically colonized patients and health care workers are the major sources of MRSA in the hospital environment. MRSA-infected patients in burns units are particularly problem...
متن کاملLaminar flow around corners triggers the formation of biofilm streamers.
Bacterial biofilms have an enormous impact on medicine, industry and ecology. These microbial communities are generally considered to adhere to surfaces or interfaces. Nevertheless, suspended filamentous biofilms, or streamers, are frequently observed in natural ecosystems where they play crucial roles by enhancing transport of nutrients and retention of suspended particles. Recent studies in s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep22372